• The two isoforms LDH A and LDH B catalyze the

  2020-08-10

  

  The two isoforms LDH-A and LDH-B catalyze the same reaction, conversion of pyruvate to lactate at the end of glycolysis. LDH-A is expressed in the liver. Humans with a hereditary deficiency of the A or B LDH isoforms are free of symptoms, except for muscle rigidity and myoglobinuria following strenu

• br Materials and Methods br Acknowledgements br Introduction

  2020-08-10

  

  Materials and Methods Acknowledgements Introduction Collagen fibrillogenesis, the assembly of collagen fibers, is a critical process in the development, maturation, and repair of mammalian tissue. Alterations in the structure and amount of deposited collagen fibers can greatly alter the int

• Cinacalcet HCl br Materials and methods br Acknowledgments

  2020-08-10

  

  Materials and methods Acknowledgments This research was supported by funding from University of California Irvine to H.U.B. Introduction Oral squamous cell carcinoma (OSCC) is the fourth major cause of mortality among men in Taiwan and its incidence rates continue to rise annually. OSCC is

• Acknowledgements This work was supported in part by

  2020-08-10

  

  Acknowledgements This work was supported in part by a Scholarship Fund for Young Researchers by the Promotion and Mutual Aid Corporation for Private (2017 to S.K.), research grant from Japan Rett Syndrome Support Organization (2018 to S.K.), and MEXT-Supported Program for the Strategic Research Fou

• In this study for the first

  2020-08-10

  

  In this TAK 165 synthesis study, for the first time, we demonstrated that herb-derived LFS-01 induces concomitant mitophagy and apoptosis in lymphoma cells. Through various biochemical studies, we showed that LFS-01 directly targets the sulfhydryl (-SH) group of a conserved cysteine in the nuclear e

• Introduction Prolyl hydroxylation is a

  2020-08-10

  

  Introduction Prolyl hydroxylation is a widely observed post translational modification in collagen, an abundant animal protein. The high content (~13% per chain of the triple helical structure) of 4-hydroxyproline (Hyp,O) in collagen, togather with the natural abundance of collagen has led to the e

• Several reasons may explain that other studies

  2020-08-10

  

  Several reasons may explain that other studies using PDE-5-Is yielded negative or contradictory results [30], [31], [32]. Lee [30] applied 50mg sildenafil to seven patients with liver cirrhosis. NO and cGMP in the hepatic membrane transport significantly increased, hepatic and pulmonary resistance

• Within the availability of large number

  2020-08-10

  

  Within the availability of large number of experimental data, it is easy to develop the relation between the mechanical strength and corrosive resistance of the RHA added cement concrete. The developed correlation is given in the following Eq. (4.8). This equation can be used to predict any of the p

• Related with the studies by

  2020-08-10

  

  Related with the studies by Zizza et al. described above [66], work by Ward et al. [68] suggested that the C2 domain of cPLA2α, which binds to zwitterionic membranes with high affinity in a Ca2+-dependent manner, has a high membrane remodeling activity, producing dramatic changes in membrane curvatu

• br Materials and methods br Results and discussion br

  2020-08-10

  

  Materials and methods Results and discussion Concluding remarks Together, the results of the theoretical kinetic simulations and of the analysis of the experimentally determined kinetic data of SoBADH performed in this work show that ignoring substrate inhibition causes potentially importan

• Previous studies in the Swiss Webster mouse Rosengren et al

  2020-08-10

  

  Previous studies in the Swiss Webster mouse (Rosengren et al., 1995) and the Sprague–Dawley rat (El Sisi et al., 1993) have shown that retinol pretreatment potentiates the hepatotoxicity of paracetamol. The current study is designed to investigate further this interaction in mice. To accomplish this

• Some limitations of this study

  2020-08-08

  

  Some limitations of this study must be noted. First, since the pretransplant evaluation of the T-cell immune response was performed just before transplantation, we cannot establish whether samples obtained at different times before the transplant would offer similar results, since end terminal disea

• Apigenin trihydroxyflavone is a flavone that has been

  2020-08-08

  

  Apigenin (4′,5,7-trihydroxyflavone), is a flavone that has been detected in a wide range of fruits, and vegetables such as bell pepper celery and cabbage. This natural flavonoid covers a broad spectrum of pharmacological activities in regard to antioxidant, anti-mutagenic, sedative, anxiolytic, and

• In the context of cellular cholesterol homeostasis

  2020-08-08

  

  In the context of cellular cholesterol homeostasis regulation of Eno1 is of particular interest. There is ample evidence pin pointing changes in ENO1 abundance as a key determinant in the transformation of macrophages to “foam cells” in response to cholesterol loading [5], [6]. Shand and West [2] de

• Talabostat mesylate In three separate studies Ferr s group p

  2020-08-07

  

  In three separate studies Ferré\'s group pointed at a relation between adenosine and its two main receptor subtypes in the Talabostat mesylate (A1R and A2AR) and brain iron deficiency (BID) in RLS. These authors found a consistent upregulation of striatal A2AR in rats and rodents with severe BID (G

15873 records 808/1059 page Previous Next First page 上5页 806807808809810 下5页 Last page