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br Experimental Procedures br Acknowledgments br
2021-05-06
Experimental Procedures Acknowledgments Introduction Bisphenol A (BPA), 2,2-bis (4-hydroxyphenyl) propane, is widely used to manufacture consumer products including food and beverage containers (Vandenberg et al., 2007). It can be accumulated in human body via leaching from the polymers int
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While showing that deletion of EP maintains femur bone
2021-05-06
While showing that deletion of EP1 maintains femur bone volume fraction and trabecular bone parameters during aging, perhaps more importantly we have also demonstrated that increased initial BV/TV in EP1 is protective against OVX-induced bone loss. That is, while mice lose an approximately equal per
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Tn5 DNA Library for 50 ng DNA br Results and discussion br C
2021-05-06
Results and discussion Conclusions In this work, we have conjugated two thermophilic enzymes (i.e., AMY and LASPO) to iron oxide NPs through different conjugation strategies obtaining efficient biocatalysts. We have demonstrated that these NP-enzyme systems can be successfully activated by an
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br Materials and methods br Results br Discussion
2021-05-06
Materials and methods Results Discussion Endothelial cells are crucial for both vascular homeostasis and protecting the vasculature against atherogenic insults [3]. OxLDL-mediated injury to endothelial cells is crucial for endothelial dysfunction in the pathogenesis of atherosclerosis and a
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br Funding This work was
2021-05-06
Funding This work was supported by the PACA Region and Avignon Université. Acknowledgements Introduction Cancer is a pivotal health problem all over the world [1]. In spite of enormous advances achieved in diagnosis and treatment over the past decades, it still accounts for over 22000 deat
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PKA signalling in the nucleus was thought
2021-05-06
PKA signalling in the nucleus was thought to be due to the translocation of the catalytic subunit upon activation from the Autophagy Compound Library to the nucleus via diffusion [72]. However, a new understanding has emerged, as both the regulatory and catalytic subunits have been identified in the
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Among the high value compounds derived from agricultural res
2021-05-06
Among the high value compounds derived from agricultural residues there are enzymes with industrial application. The extraction processes have been focused on the development of new strategies that guarantee high recovery rates with maximum activity (Nadar et al., 2017). The residues of these two fr
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br Conclusions br Introduction The terms endocrine
2021-05-06
Conclusions Introduction The terms endocrine active and endocrine disruptive have been used to describe an ever-expanding list of naturally-occurring and synthetic compounds that interact with mammalian hormonal systems, and in particular, the reproductive system. These compounds have been ass
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In conclusion we have shown that the
2021-05-06
In conclusion, we have shown that the cellular effects produced by SFN in NSCLC silybin mg are largely mediated by SFN-induced production of ROS. Cells with higher levels of EGFR were more resistant to SFN treatment and showed resistance to SFN-induced apoptosis, suggesting that high EGFR levels pro
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Across the scaffold the platform anchors the
2021-05-06
Across the scaffold, the platform anchors the N terminus of the elongated cullin structure of APC2 [21]. This connects to the flexible cullin–RING catalytic core consisting of the C-terminal region of APC2 and the associated APC11 11, 12, 21. The flexibility and positions of the catalytic core are c
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One of the most fundamental distinctions between Ub signals
2021-05-06
One of the most fundamental distinctions between Ub signals is substrate monoubiquitination versus polyubiquitination. With the exception of the E2, UBE2W, which represents a special case because it cetp inhibitors only ubiquitinates the flexible N-termini of substrates [5], [6], [20], most example
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br Conclusion As far as we know this work constituted
2021-05-06
Conclusion As far as we know, this work constituted the first use of silver nitrate staining and sequential FISH in V. vinifera. This technique allowed the unequivocal identification of Ag-NORs and corresponding rDNA loci. Besides, silver nitrate staining and sequential FISH may bring new insight
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br Experimental section br Results and discussion br Conclus
2021-05-06
Experimental section Results and discussion Conclusions In conclusion, we have presented an autocatalytic recycling amplification electrochemical biosensing platform for simple, rapid and ultrasensitive detection of MTase activity by combining methylation-sensitive restriction endonuclease
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br Results and discussion To check
2021-05-06
Results and discussion To check the Nitrocefin receptor that the charge of α-synuclein can be altered due to the glycation, we measured zeta potential of native α-synuclein and α-synuclein glycated by two different glycating agents, methylglyoxal (MG) and glyceraldehyde-3-phosphate (GA-3-P). The
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Here we also took attempt to evaluate the CYP mediated
2021-05-05
Here we also took attempt to evaluate the CYP mediated inhibition potential of S. chirata and its biomarker ursolic Crystal Violet on pooled RLM by CYP-CO complex assay. We observed that S. chirata extract and ursolic acid showed less enzyme inhibition than known inhibitor (ketoconazole). It exhibi
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