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br Growth supportive characteristics of the BM vascular nich
2019-06-14

Growth-supportive characteristics of the BM vascular niche Similar to normal tissues, tumours also need functional blood vessels to support their growth via the delivery of oxygen and nutrients. When a DTC starts proliferating into a micrometastasis, it drives angiogenesis to build new blood vess
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The clinical spectrum of intracranial hemorrhage
2019-06-14

The clinical spectrum of intracranial hemorrhage is similar for patients treated with warfarin and dabigatran [10]. Absolute rates of intracranial hemorrhage across all sites and of both fatal and traumatic intracranial hemorrhages are lower with dabigatran than with warfarin [10]. Concomitant aspir
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guanidine hydrochloride br Other drugs Overdose of diphenhyd
2019-06-14

Other drugs Overdose of diphenhydramine (an H1 histamine receptor antagonist) is reported to induce a BrS phenotype [58,59]. Antihistamines are known to cause QT prolongation secondary to IKr inhibition. Cocaine is known to block the sodium guanidine hydrochloride and thus to unmask a BrS phenot
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br Discussion This patient presented with a rare case of
2019-06-14

Discussion This patient presented with a rare case of ameboma and underwent a right hemicolectomy procedure. However, the patient did not survive the surgical intervention and post-operative period due to severe sepsis. The primary reason that treatment failed was due to delayed diagnosis and tre
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br Radiotherapy for bone metastases As a palliative
2019-06-14

Radiotherapy for bone metastases As a palliative intervention, radiotherapy is effective and efficient at treating painful bone metastases, and the side effects associated with its use are manageable and usually self-limiting in nature. Between 50% and 80% of patients gain at least partial relief
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br Genetic basis for atrial standstill br Genetic basis
2019-06-14

Genetic basis for atrial standstill Genetic basis of conduction block Genes involved in cardiac development and bradycardia Development of the CCS is a complex biological process with the potential to be wrought with problems. Several transcription factors, including homeodomain proteins an
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The aim of this cross
2019-06-14

The aim of this cross-sectional study was to investigate the relationships between patient characteristics and antithrombotic therapy prescribed for the prevention of ischemic stroke and systemic embolism in patients with NVAF in clinical practice. Additionally, because the data were to be used to c
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br The Oct Comment by Chris
2019-06-14

The Oct 17 Comment by Chris Collins and Chris Beyrer raises several important challenges associated with strengthening country ownership and accelerating progress in the global HIV/AIDS response. Working together with our partners, the US President\'s Emergency Plan for AIDS Relief (PEPFAR) is fir
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Stigma and discrimination experienced by sex
2019-06-14

Stigma and discrimination experienced by sex workers, injection drug users, and men who have sex with men is tough to tackle. Responses need to be tailored to very different circumstances and require interventions on several levels: policy, societal, health system, and individual. There is no magic
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It means an opportunity As
2019-06-14

It means an opportunity. As we concern ourselves with the prominence of health in the new agenda, it\'s easy to forget that (human) development is by definition people-centred, and that living a long, healthy, and creative life is its cornerstone. The expansion of the new goals to encompass many (if
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br LEGADO FUJIMORISTA No seu
2019-06-14

LEGADO FUJIMORISTA No seu segundo mandato, García abandonou as veleidades esquerdistas realizando um governo abertamente neoliberal. Embora em campanha criticasse o modelo de exploração mineira em que se assentava o crescimento peruano, praticamente eximindo as empresas de obrigações tributárias
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One year after her initial diagnosis the patient presented
2019-06-14

One year after her initial diagnosis, the patient presented back for the abrupt onset of symmetrical bilateral lower-limb weakness and numbness. The patient did not report other symptoms or history of trauma. Clinical examination revealed a healthy person except for a symmetrical proximal and distal
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Flow cytometric immunophenotyping showed the circulating bla
2019-06-14

Flow cytometric immunophenotyping showed the circulating blasts expressed CD19, CD20, CD22, CD24 partial, HLA -DR, CD34, and TdT. There was variable expression of the myeloid markers CD15 and CD33. The blasts were negative for CD3, CD10, MPO, and all other T-cell, myeloid, and monocytic markers eval
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Clofarabine associated capillary leak syndrome attributed
2019-06-14

Clofarabine-associated capillary leak syndrome, attributed to cytokine release, is characterized by hypotension, tachycardia, and tachypnea, and can be fatal. Alternatively, Type I hypersensitivity to clofarabine can occur in up to 5% of patients, and is also a contraindication to further therapy pe
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exportin Significant uncertainty remains about the precise v
2019-06-14

Significant uncertainty remains about the precise vectors, the plasticity of vector host-selection (ie, monkey human) and the exact location of vector exposure that results in human transmission of especially across different parts of Asia. In particular, uncertainty exists as to whether transmiss
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