• br Radiotherapy for bone metastases As a palliative

  2019-06-14

  

  Radiotherapy for bone metastases As a palliative intervention, radiotherapy is effective and efficient at treating painful bone metastases, and the side effects associated with its use are manageable and usually self-limiting in nature. Between 50% and 80% of patients gain at least partial relief

• br Genetic basis for atrial standstill br Genetic basis

  2019-06-14

  

  Genetic basis for atrial standstill Genetic basis of conduction block Genes involved in cardiac development and bradycardia Development of the CCS is a complex biological process with the potential to be wrought with problems. Several transcription factors, including homeodomain proteins an

• The aim of this cross

  2019-06-14

  

  The aim of this cross-sectional study was to investigate the relationships between patient characteristics and antithrombotic therapy prescribed for the prevention of ischemic stroke and systemic embolism in patients with NVAF in clinical practice. Additionally, because the data were to be used to c

• br The Oct Comment by Chris

  2019-06-14

  

  The Oct 17 Comment by Chris Collins and Chris Beyrer raises several important challenges associated with strengthening country ownership and accelerating progress in the global HIV/AIDS response. Working together with our partners, the US President\'s Emergency Plan for AIDS Relief (PEPFAR) is fir

• Stigma and discrimination experienced by sex

  2019-06-14

  

  Stigma and discrimination experienced by sex workers, injection drug users, and men who have sex with men is tough to tackle. Responses need to be tailored to very different circumstances and require interventions on several levels: policy, societal, health system, and individual. There is no magic

• It means an opportunity As

  2019-06-14

  

  It means an opportunity. As we concern ourselves with the prominence of health in the new agenda, it\'s easy to forget that (human) development is by definition people-centred, and that living a long, healthy, and creative life is its cornerstone. The expansion of the new goals to encompass many (if

• br LEGADO FUJIMORISTA No seu

  2019-06-14

  

  LEGADO FUJIMORISTA No seu segundo mandato, García abandonou as veleidades esquerdistas realizando um governo abertamente neoliberal. Embora em campanha criticasse o modelo de exploração mineira em que se assentava o crescimento peruano, praticamente eximindo as empresas de obrigações tributárias

• One year after her initial diagnosis the patient presented

  2019-06-14

  

  One year after her initial diagnosis, the patient presented back for the abrupt onset of symmetrical bilateral lower-limb weakness and numbness. The patient did not report other symptoms or history of trauma. Clinical examination revealed a healthy person except for a symmetrical proximal and distal

• Flow cytometric immunophenotyping showed the circulating bla

  2019-06-14

  

  Flow cytometric immunophenotyping showed the circulating blasts expressed CD19, CD20, CD22, CD24 partial, HLA -DR, CD34, and TdT. There was variable expression of the myeloid markers CD15 and CD33. The blasts were negative for CD3, CD10, MPO, and all other T-cell, myeloid, and monocytic markers eval

• Clofarabine associated capillary leak syndrome attributed

  2019-06-14

  

  Clofarabine-associated capillary leak syndrome, attributed to cytokine release, is characterized by hypotension, tachycardia, and tachypnea, and can be fatal. Alternatively, Type I hypersensitivity to clofarabine can occur in up to 5% of patients, and is also a contraindication to further therapy pe

• exportin Significant uncertainty remains about the precise v

  2019-06-14

  

  Significant uncertainty remains about the precise vectors, the plasticity of vector host-selection (ie, monkey human) and the exact location of vector exposure that results in human transmission of especially across different parts of Asia. In particular, uncertainty exists as to whether transmiss

• br The slow progress in endemicity mapping of neglected

  2019-06-14

  

  The slow progress in endemicity mapping of neglected tropical diseases (NTDs) in Africa and scaling up of mass drug administration (MDA) in all endemic countries has hampered efforts to meet the London 2020 elimination and control targets. Lymphatic filariasis is targeted to be eliminated by 2020;

• What lies ahead Clearly the extremely

  2019-06-14

  

  What lies ahead? Clearly the extremely ambitious goals and targets set by the UNCoLSC have not been reached, and challenges must be overcome. While the current evaluation highlights several challenges and strategies for action, a clear process in moving forward would be to link this bottleneck analy

• br Conflict of interest br Acknowledgments br Introduction C

  2019-06-13

  

  Conflict of interest Acknowledgments Introduction Compared to the traditional right atrial appendage (RAA) pacing, inferior interatrial septum (IAS) pacing around the coronary sinus ostium significantly reduces paroxysmal atrial fibrillation (AF) burden and recurrence and slows the progress

• br The L type calcium

  2019-06-13

  

  The L-type calcium channel (LTCC) in heart consists of 4 subunits: α1, β2, α2, and δ [47], encoded by CACNA1C, CACNB2, and CACNA2D, respectively, with the α2 and δ subunits encoded by the gene CANA2D. In 2007, Antzelevitch et al. [48] reported 2 CACNA1C mutations and a CACNB2 mutation from a genot

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