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Major outcomes from MADIT II trial
2019-04-26
Major outcomes from MADIT-II trial suggested that, once again, the risk of death in defibrillator group was significantly less than conventional-therapy group with hazard ratio of 0.69. In this trial, the major drawback was corrected. The medication use remained balanced between ICD patients, and co
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Introduction Ewing s sarcoma ES
2019-04-26
Introduction Ewing\'s sarcoma (ES) is a high-grade neoplasm representing the second most common primary bone malignancy in both children and adults. With a peak incidence at 15 years, this disease accounts for 2% of childhood cancers [1–3]. ES is defined as a bone tumor which may occur at any site
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Era tal el recelo que hab a
2019-04-26
Era tal el recelo que había sobre el enriquecimiento de los ministros que en enero de 1622 se intentó investigar los orígenes de su riqueza. El mismo mes se publicó un decreto que estipulaba que todos los que habían tenido cargos HOBt Supplier partir de 1592 debían inventariar sus propiedades ante u
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br Results br Discussion We identified a novel heterozygous
2019-04-26
Results Discussion We identified a novel, heterozygous nonsense SCN5A mutation, Q779X, in a family with overlapped phenotype with progressive conduction defects and BrS. The proband suffered from SSS at the age of three, and subsequent ventricular fibrillation with a coved type Brugada ECG pat
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All cases of obstetric fistula
2019-04-26
All cases of obstetric fistula can be prevented with timely access to emergency obstetric care, especially caesarean section. Obstetric fistula was virtually eliminated in Europe and the USA between 1935 and 1950, because of universal access to safe delivery care. That it is still a public health pr
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br We recently reported associations between maternal age at
2019-04-26
We recently reported associations between maternal age at childbirth and outcomes in the offspring, using data from five birth cohorts (COHORTS collaboration) in low-income and middle-income countries (LMICs), in . Young maternal age ( associations were independent of maternal socioeconomic status
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br Discussion In the present report
2019-04-26
Discussion In the present report, we describe a technique for the rifampicin of a 6.0 Fr active fixation atrial lead in the inferior IAS using a 9.0 Fr GC. Previous studies have indicated that inferior IAS pacing significantly reduces paroxysmal AF burden and recurrence and slows the progression
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br Monitoring coagulation levels Coagulation levels can be m
2019-04-26
Monitoring coagulation levels Coagulation levels can be monitored after warfarin treatment by measuring the prothrombin time (PT). However, monitoring is not needed for novel anticoagulants because these drugs have a much wider therapeutic range than warfarin. Nonetheless, in patients at high ris
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br Case report A years old man
2019-04-26
Case report A 51-years-old man visited our hospital presenting with a palpable mass over the right inguinal area which had persisted for 3 months. This lesion was approximately 3–4 cm, firm and had progressively enlarged. Laboratory data showed no remarkable anomaly except elevated lactate dehydr
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Cell adhesion to extracellular matrix requires the
2019-04-26
Cell adhesion to extracellular matrix requires the interaction of different molecules like selectins, cadherins and integrins [21]. Especially αvβ3 integrin has been proposed to mediate the adhesion of malignant cells in different entities such as multiple myeloma and breast cancer [22,23]. Upon exp
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br The west African outbreak of Ebola virus disease is
2019-04-25
The 2014–15 west African outbreak of Ebola virus disease is unprecedented in scale, especially in Sierra Leone, which as of May 15, 2015, had reported 8598 confirmed cases and 3538 confirmed Ebola-related deaths. Sierra Leone\'s response to this emergency has been compromised by a fragile health s
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Tricot muestra las entra as del Movimiento Mapuche
2019-04-25
Tricot muestra las entrañas del Movimiento Mapuche Autonomista con la intención de conducir al lector en la comprensión de la resistencia actual de autoafirmación “ora como pueblo-nación, ora como Identidad Territorial específica”; afirma que el movimiento mapuche “no es un proceso lineal, sino más
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onde introduzimos a negritude como uma concep
2019-04-25
É onde introduzimos pten pathway negritude como uma concepção adotada pelos intelectuais e movimentos sociais ligados à causa negra no Brasil. A negritude foi conceituada por seu criador, o poeta e intelectual Aimé Cesairé, como “o simples reconhecimento do fato de ser negro, a aceitação de seu dest
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Premature deaths of women have
2019-04-25
Premature deaths of women have profound effects on families, societies, and economies, regardless of the age at which they occur and whatever the cause, including an—often preventable—NCD or injury later in life. Families, especially if female-headed, are driven into poverty through catastrophic hea
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After a decade of political and economic crisis between
2019-04-25
After a decade of political and economic crisis between 1999 and 2010, health education in Zimbabwe was in a desperate state and required a major overhaul. UZCHS reported a 60% decrease in medical student enrolment, a 61% faculty vacancy rate, a 50% increase in failure rate, and the specialist train
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